Established in 2011, the Australian Infectious Diseases Research Centre is a multidisciplinary network based at The University of Queensland, and the Queensland Institute of Medical Research.
Dr. Kate Schroder (NHMRC CJ Martin Fellow)
Dr. Kate Schroder investigates the pathways that trigger activation of the innate immune system.
In particular, she studies signalling by an emerging player in innate immunity called the ‘inflammasome’, a cellular detection system that mediates cytokine maturation and immune system activation in response to host- and pathogen-derived ‘danger’ signals.
While inflammasome activation is protective against infection, clinical and experimental data suggest it mediates a common disease-driving pathway in surprisingly wide variety of hereditary and acquired diseases (e.g. hereditary fever syndromes, gout, type 1 and 2 diabetes, various arthritic diseases).
Dr. Schroder’s research characterises the role of inflammasomes in both auto-inflammatory disease and host protection against infection.
Publications by Kate Schroder