2018: 

Alhallaf, R., Agha, Z., Miller, C.M., Robertson, A.A.B., Sotillo, J., Croese, J., Cooper, M.A., Masters, S.L., Kupz, A., Smith, N.C., Loukas, A. and Giacomin, P.R. (2018) The NLRP3 inflammasome suppresses protective immunity to gastrointestinal helminth infection. Cell reports 23: 10.1016/j.celrep.2018.03.097

 

Blaskovich, M.A.T., Hansford, K.A., Gong, Y., Butler, M.S., Muldoon, C., Huang, J.X., Ramu, S., Silva, A.B., Cheng, M., Kavanagh, A.M., Ziora, Z., Premraj, R., Lindahl, F., Bradford, T.A., Lee, J.C., Karoli, T., Pelingon, R., Edwards, D.J., Amado, M., Elliott, A.G., Phetsang, W., Daud, N.H., Deecke, J.E., Sidjabat, H.E., Ramaologa, S., Zuegg, J., Betley, J.R., Beevers, A.P.G., Smith, R.A.G., Roberts, J.A., Paterson, D.L. and Cooper, M.A. (2018) Protein-inspired antibiotics active against vancomycin- and daptomycin-resistant bacteria. Nature communications 9: 10.1038/s41467-017-02123-w

 

Boyd, M.A., Cooper, D.A. and Gilks, C.F. (2018) Towards a universal second-line fixed-dose combination ART. The lancet. HIV 5: 10.1016/s2352-3018(17)30180-7

 

Chang, A.B., Bush, A. and Grimwood, K. (2018) Bronchiectasis in children: diagnosis and treatment. Lancet (London, England) 392: 10.1016/s0140-6736(18)31554-x

 

Chen, K.W., Monteleone, M., Boucher, D., Sollberger, G., Ramnath, D., Condon, N.D., von Pein, J.B., Broz, P., Sweet, M.J. and Schroder, K. (2018) Noncanonical inflammasome signaling elicits gasdermin D-dependent neutrophil extracellular traps. Science immunology 3: 10.1126/sciimmunol.aar6676

 

Collins, K.A., Wang, C.Y., Adams, M., Mitchell, H., Rampton, M., Elliott, S., Reuling, I.J., Bousema, T., Sauerwein, R., Chalon, S., Mohrle, J.J. and McCarthy, J.S. (2018) A controlled human malaria infection model enabling evaluation of transmission-blocking interventions. The Journal of clinical investigation 128: 10.1172/jci98012

 

Corbin, L.J., Tan, V.Y., Hughes, D.A., Wade, K.H., Paul, D.S., Tansey, K.E., Butcher, F., Dudbridge, F., Howson, J.M., Jallow, M.W., John, C., Kingston, N., Lindgren, C.M., O'Donavan, M., O'Rahilly, S., Owen, M.J., Palmer, C.N.A., Pearson, E.R., Scott, R.A., van Heel, D.A., Whittaker, J., Frayling, T., Tobin, M.D., Wain, L.V., Smith, G.D., Evans, D.M., Karpe, F., McCarthy, M.I., Danesh, J., Franks, P.W. and Timpson, N.J. (2018) Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference. Nature communications 9: 10.1038/s41467-018-03109-y

 

Duffy, D.L., Zhu, G., Li, X., Sanna, M., Iles, M.M., Jacobs, L.C., Evans, D.M., Yazar, S., Beesley, J., Law, M.H., Kraft, P., Visconti, A., Taylor, J.C., Lui, F., Wright, M.J., Henders, A.K., Bowdler, L., Glass, D., Ikram, A.M., Uitterlinden, A.G., Madden, P.A., Heath, A.C., Nelson, E.C., Green, A.C., Chanock, S., Barrett, J.H., Brown, M.A., Hayward, N.K., MacGregor, S., Sturm, R.A., Hewitt, A.W., Kayser, M., Hunter, D.J., Newton Bishop, J.A., Spector, T.D., Montgomery, G.W., Mackey, D.A., Smith, G.D., Nijsten, T.E., Bishop, D.T., Bataille, V., Falchi, M., Han, J. and Martin, N.G. (2018) Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways. Nature communications 9: 10.1038/s41467-018-06649-5

 

Fleischmann-Struzek, C., Goldfarb, D.M., Schlattmann, P., Schlapbach, L.J., Reinhart, K. and Kissoon, N. (2018) The global burden of paediatric and neonatal sepsis: a systematic review. The Lancet. Respiratory medicine 6: 10.1016/s2213-2600(18)30063-8

 

Franklin, D., Babl, F.E., Schlapbach, L.J., Oakley, E., Craig, S., Neutze, J., Furyk, J., Fraser, J.F., Jones, M., Whitty, J.A., Dalziel, S.R. and Schibler, A. (2018) A randomized trial of high-flow oxygen therapy in infants with bronchiolitis. The New England journal of medicine 378: 10.1056/NEJMoa1714855

 

Garcia, M.D., Chua, S.M.H., Low, Y.S., Lee, Y.T., Agnew-Francis, K., Wang, J.G., Nouwens, A., Lonhienne, T., Williams, C.M., Fraser, J.A. and Guddat, L.W. (2018) Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections. Proceedings of the National Academy of Sciences of the United States of America 115: 10.1073/pnas.1809422115

 

Gong, H., Li, J., Xu, A., Tang, Y., Ji, W., Gao, R., Wang, S., Yu, L., Tian, C., Li, J., Yen, H.Y., Man Lam, S., Shui, G., Yang, X., Sun, Y., Li, X., Jia, M., Yang, C., Jiang, B., Lou, Z., Robinson, C.V., Wong, L.L., Guddat, L.W., Sun, F., Wang, Q. and Rao, Z. (2018) An electron transfer path connects subunits of a mycobacterial respiratory supercomplex. Science (New York, N.Y.) 362: 10.1126/science.aat8923

 

Gordon, R., Albornoz, E.A., Christie, D.C., Langley, M.R., Kumar, V., Mantovani, S., Robertson, A.A.B., Butler, M.S., Rowe, D.B., O'Neill, L.A., Kanthasamy, A.G., Schroder, K.Cooper, M.A. and Woodruff, T.M. (2018) Inflammasome inhibition prevents alpha-synuclein pathology and dopaminergic neurodegeneration in mice. Science translational medicine 10: 10.1126/scitranslmed.aah4066

 

Goyal, V., Grimwood, K., Byrnes, C.A., Morris, P.S., Masters, I.B., Ware, R.S., McCallum, G.B., Binks, M.J., Marchant, J.M., van Asperen, P., O'Grady, K.F., Champion, A., Buntain, H.M., Petsky, H., Torzillo, P.J. and Chang, A.B. (2018) Amoxicillin-clavulanate versus azithromycin for respiratory exacerbations in children with bronchiectasis (BEST-2): a multicentre, double-blind, non-inferiority, randomised controlled trial. Lancet (London, England) 392: 10.1016/s0140-6736(18)31723-9

 

Guy, R.J., Ward, J., Causer, L.M., Natoli, L., Badman, S.G., Tangey, A., Hengel, B., Wand, H., Whiley, D., Tabrizi, S.N., Shephard, M., Fairley, C.K., Donovan, B., Anderson, D.A., Regan, D.G., Maher, L. and Kaldor, J.M. (2018) Molecular point-of-care testing for chlamydia and gonorrhoea in Indigenous Australians attending remote primary health services (TTANGO): a cluster-randomised, controlled, crossover trial. The Lancet. Infectious diseases 18: 10.1016/s1473-3099(18)30429-8

 

Hall, M.T., Simms, K.T., Lew, J.B., Smith, M.A., Brotherton, J.M., Saville, M., Frazer, I.H. and Canfell, K. (2018) The projected timeframe until cervical cancer elimination in Australia: a modelling study. The Lancet. Public health 4: 10.1016/s2468-2667(18)30183-x

 

Harris, P.N.A., Tambyah, P.A., Lye, D.C., Mo, Y., Lee, T.H., Yilmaz, M., Alenazi, T.H., Arabi, Y., Falcone, M., Bassetti, M., Righi, E., Rogers, B.A., Kanj, S., Bhally, H., Iredell, J., Mendelson, M., Boyles, T.H., Looke, D., Miyakis, S., Walls, G., Al Khamis, M., Zikri, A., Crowe, A., Ingram, P., Daneman, N., Griffin, P., Athan, E., Lorenc, P., Baker, P., Roberts, L., Beatson, S.A., Peleg, A.Y., Harris-Brown, T. and Paterson, D.L. (2018) Effect of piperacillin-tazobactam vs meropenem on 30-day mortality for patients with E. coli or Klebsiella pneumoniae bloodstream infection and ceftriaxone resistance: a randomized clinical trial. Jama 320: 10.1001/jama.2018.12163

 

Holley, C.L., Coll, R.C. and Schroder, K. (2018) NLRC3 restrains responses to a T. Immunity 49: 10.1016/j.immuni.2018.12.003

 

Imai, T., Matsumura, T., Mayer-Lambertz, S., Wells, C.A., Ishikawa, E., Butcher, S.K., Barnett, T.C., Walker, M.J., Imamura, A., Ishida, H., Ikebe, T., Miyamoto, T., Ato, M., Ohga, S., Lepenies, B., van Sorge, N.M. and Yamasaki, S. (2018) Lipoteichoic acid anchor triggers Mincle to drive protective immunity against invasive group A Streptococcus infection. Proceedings of the National Academy of Sciences of the United States of America 115: 10.1073/pnas.1809100115

 

Kovtun, O., Leneva, N., Bykov, Y.S., Ariotti, N., Teasdale, R.D., Schaffer, M., Engel, B.D., Owen, D.J., Briggs, J.A.G. and Collins, B.M. (2018) Structure of the membrane-assembled retromer coat determined by cryo-electron tomography. Nature 561: 10.1038/s41586-018-0526-z

 

Lee, H.J., Georgiadou, A., Walther, M., Nwakanma, D., Stewart, L.B., Levin, M., Otto, T.D., Conway, D.J., Coin, L.J. and Cunnington, A.J. (2018) Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria. Science translational medicine 10: 10.1126/scitranslmed.aar3619

 

Lober, U., Hobbs, M., Dayaram, A., Tsangaras, K., Jones, K., Alquezar-Planas, D.E., Ishida, Y., Meers, J., Mayer, J., Quedenau, C., Chen, W., Johnson, R.N., Timms, P., Young, P.R., Roca, A.L. and Greenwood, A.D. (2018) Degradation and remobilization of endogenous retroviruses by recombination during the earliest stages of a germ-line invasion. Proceedings of the National Academy of Sciences of the United States of America 115: 10.1073/pnas.1807598115

 

Lonhienne, T., Garcia, M.D., Pierens, G., Mobli, M., Nouwens, A. and Guddat, L.W. (2018) Structural insights into the mechanism of inhibition of AHAS by herbicides. Proceedings of the National Academy of Sciences of the United States of America 115: 10.1073/pnas.1714392115

 

Luo, L., Wall, A.A., Tong, S.J., Hung, Y., Xiao, Z., Tarique, A.A., Sly, P.D., Fantino, E., Marzolo, M.P. and Stow, J.L. (2018) TLR crosstalk activates LRP1 to recruit Rab8a and PI3Kgamma for suppression of inflammatory responses. Cell reports 24: 10.1016/j.celrep.2018.08.028

 

Lynch, J.P., Werder, R.B., Loh, Z., Sikder, M.A.A., Curren, B., Zhang, V., Rogers, M.J., Lane, K., Simpson, J., Mazzone, S.B., Spann, K., Hayball, J., Diener, K., Everard, M.L., Blyth, C.C., Forstner, C., Dennis, P.G., Murtaza, N., Morrison, M., P, O.C., Zhang, P., Haque, A., Hill, G.R., Sly, P.D., Upham, J.W. and Phipps, S. (2018) Plasmacytoid dendritic cells protect from viral bronchiolitis and asthma through semaphorin 4a-mediated T reg expansion. The Journal of experimental medicine 215: 10.1084/jem.20170298

 

Martinon-Torres, F., Salas, A., Rivero-Calle, I., Cebey-Lopez, M., Pardo-Seco, J., Herberg, J.A., Boeddha, N.P., Klobassa, D.S., Secka, F., Paulus, S., de Groot, R., Schlapbach, L.J., Driessen, G.J., Anderson, S.T., Emonts, M., Zenz, W., Carrol, E.D., Van der Flier, M. and Levin, M. (2018) Life-threatening infections in children in Europe (the EUCLIDS Project): a prospective cohort study. The Lancet. Child & adolescent health 2: 10.1016/s2352-4642(18)30113-5

 

McManus, D.P., Dunne, D.W., Sacko, M., Utzinger, J., Vennervald, B.J. and Zhou, X.N. (2018) Schistosomiasis. Nature reviews. Disease primers 4: 10.1038/s41572-018-0013-8

 

Miles, J.J., Tan, M.P., Dolton, G., Edwards, E.S., Galloway, S.A., Laugel, B., Clement, M., Makinde, J., Ladell, K., Matthews, K.K., Watkins, T.S., Tungatt, K., Wong, Y., Lee, H.S., Clark, R.J., Pentier, J.M., Attaf, M., Lissina, A., Ager, A., Gallimore, A., Rizkallah, P.J., Gras, S., Rossjohn, J., Burrows, S.R., Cole, D.K., Price, D.A. and Sewell, A.K. (2018) Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry. The Journal of clinical investigation 128: 10.1172/jci91512

 

Monteiro, M.J. (2018) Order from disorder through dissipation of free energy. Nature nanotechnology 13: 10.1038/s41565-018-0220-1

 

Monteleone, M., Stanley, A.C., Chen, K.W., Brown, D.L., Bezbradica, J.S., von Pein, J.B., Holley, C.L., Boucher, D., Shakespear, M.R., Kapetanovic, R., Rolfes, V., Sweet, M.J.Stow, J.L. and Schroder, K. (2018) Interleukin-1beta maturation triggers its relocation to the plasma membrane for gasdermin-D-dependent and -independent secretion. Cell reports 24: 10.1016/j.celrep.2018.07.027

 

Nguyen, H., Kuril, S., Bastian, D., Kim, J., Zhang, M., Vaena, S.G., Dany, M., Dai, M., Heinrichs, J.L., Daenthanasanmak, A., Iamsawat, S., Schutt, S., Fu, J., Wu, Y., Fairlie, D.P., Atkinson, C., Ogretmen, B., Tomlinson, S. and Yu, X.Z. (2018) Complement C3a and C5a receptors promote GVHD by suppressing mitophagy in recipient dendritic cells. JCI insight 3: 10.1172/jci.insight.121697

 

O'Neill, L.A. and Cooper, M.A. (2018) Canakinumab for atherosclerotic disease. The New England journal of medicine 378: 10.1056/NEJMc1714635

 

Pavord, I.D., Beasley, R., Agusti, A., Anderson, G.P., Bel, E., Brusselle, G., Cullinan, P., Custovic, A., Ducharme, F.M., Fahy, J.V., Frey, U., Gibson, P., Heaney, L.G., Holt, P.G., Humbert, M., Lloyd, C.M., Marks, G., Martinez, F.D., Sly, P.D., von Mutius, E., Wenzel, S., Zar, H.J. and Bush, A. (2018) After asthma: redefining airways diseases. The Lancet 391: 10.1016/s0140-6736(17)30879-6

 

Pender, M.P., Csurhes, P.A., Smith, C., Douglas, N.L., Neller, M.A., Matthews, K.K., Beagley, L., Rehan, S., Crooks, P., Hopkins, T.J., Blum, S., Green, K.A., Ioannides, Z.A., Swayne, A., Aftab, B.T., Hooper, K.D., Burrows, S.R., Thompson, K.M., Coulthard, A. and Khanna, R. (2018) Epstein-Barr virus-specific T cell therapy for progressive multiple sclerosis. JCI insight 3: 10.1172/jci.insight.124714

 

Prow, N.A., Liu, L., Nakayama, E., Cooper, T.H., Yan, K., Eldi, P., Hazlewood, J.E., Tang, B., Le, T.T., Setoh, Y.X., Khromykh, A.A., Hobson-Peters, J., Diener, K.R., Howley, P.M., Hayball, J.D. and Suhrbier, A. (2018) A vaccinia-based single vector construct multi-pathogen vaccine protects against both Zika and chikungunya viruses. Nature communications 9: 10.1038/s41467-018-03662-6

 

Ramnath, D., Irvine, K.M., Lukowski, S.W., Horsfall, L.U., Loh, Z., Clouston, A.D., Patel, P.J., Fagan, K.J., Iyer, A., Lampe, G., Stow, J.L.Schroder, K.Fairlie, D.P., Powell, J.E., Powell, E.E. and Sweet, M.J. (2018) Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes. JCI insight 3: 10.1172/jci.insight.120274

 

Regan, D.G., Hui, B.B., Wood, J.G., Fifer, H., Lahra, M.M. and Whiley, D.M. (2018) Treatment for pharyngeal gonorrhoea under threat. The Lancet. Infectious diseases 18: 10.1016/s1473-3099(18)30610-8

 

Rosenfeld, M., Wainwright, C.E., Higgins, M., Wang, L.T., McKee, C., Campbell, D., Tian, S., Schneider, J., Cunningham, S. and Davies, J.C. (2018) Ivacaftor treatment of cystic fibrosis in children aged 12 to <24 months and with a CFTR gating mutation (ARRIVAL): a phase 3 single-arm study. The Lancet. Respiratory medicine 6: 10.1016/s2213-2600(18)30202-9

 

Roux, S., Adriaenssens, E.M., Dutilh, B.E., Koonin, E.V., Kropinski, A.M., Krupovic, M., Kuhn, J.H., Lavigne, R., Brister, J.R., Varsani, A., Amid, C., Aziz, R.K., Bordenstein, S.R., Bork, P., Breitbart, M., Cochrane, G.R., Daly, R.A., Desnues, C., Duhaime, M.B., Emerson, J.B., Enault, F., Fuhrman, J.A., Hingamp, P., Hugenholtz, P., Hurwitz, B.L., Ivanova, N.N., Labonte, J.M., Lee, K.B., Malmstrom, R.R., Martinez-Garcia, M., Mizrachi, I.K., Ogata, H., Paez-Espino, D., Petit, M.A., Putonti, C., Rattei, T., Reyes, A., Rodriguez-Valera, F., Rosario, K., Schriml, L., Schulz, F., Steward, G.F., Sullivan, M.B., Sunagawa, S., Suttle, C.A., Temperton, B., Tringe, S.G., Thurber, R.V., Webster, N.S., Whiteson, K.L., Wilhelm, S.W., Wommack, K.E., Woyke, T., Wrighton, K.C., Yilmaz, P., Yoshida, T., Young, M.J., Yutin, N., Allen, L.Z., Kyrpides, N.C. and Eloe-Fadrosh, E.A. (2018) Minimum information about an uncultivated virus genome (MIUViG). Nature biotechnology 10.1038/nbt.4306

 

Roy Chowdhury, R., Vallania, F., Yang, Q., Lopez Angel, C.J., Darboe, F., Penn-Nicholson, A., Rozot, V., Nemes, E., Malherbe, S.T., Ronacher, K., Walzl, G., Hanekom, W., Davis, M.M., Winter, J., Chen, X., Scriba, T.J., Khatri, P. and Chien, Y.H. (2018) A multi-cohort study of the immune factors associated with M. tuberculosis infection outcomes. Nature 560: 10.1038/s41586-018-0439-x

 

Schlapbach, L.J. and Kissoon, N. (2018) Defining pediatric sepsis. JAMA pediatrics 172: 10.1001/jamapediatrics.2017.5208

 

Sina, A.A., Carrascosa, L.G., Liang, Z., Grewal, Y.S., Wardiana, A., Shiddiky, M.J.A., Gardiner, R.A., Samaratunga, H., Gandhi, M.K., Scott, R.J., Korbie, D. and Trau, M. (2018) Epigenetically reprogrammed methylation landscape drives the DNA self-assembly and serves as a universal cancer biomarker. Nature communications 9: 10.1038/s41467-018-07214-w

 

Sipp, D., Frazer, I.H. and Rasko, J.E.J. (2018) No vacillation on HPV vaccination. Cell 172: 10.1016/j.cell.2018.02.045

 

Soderholm, A.T. and Walker, M.J. (2018) A host proteome atlas of Streptococcus pyogenes infection. Cell systems 6: 10.1016/j.cels.2018.05.003

 

Teo, S.M., Tang, H.H.F., Mok, D., Judd, L.M., Watts, S.C., Pham, K., Holt, B.J., Kusel, M., Serralha, M., Troy, N., Bochkov, Y.A., Grindle, K., Lemanske, R.F., Jr., Johnston, S.L., Gern, J.E., Sly, P.D., Holt, P.G., Holt, K.E. and Inouye, M. (2018) Airway microbiota dynamics uncover a critical window for interplay of pathogenic bacteria and allergy in childhood respiratory disease. Cell host & microbe 24: 10.1016/j.chom.2018.08.005

 

Tsao, S.C., Wang, J., Wang, Y., Behren, A., Cebon, J. and Trau, M. (2018) Characterising the phenotypic evolution of circulating tumour cells during treatment. Nature communications 9: 10.1038/s41467-018-03725-8

 

Varelias, A., Bunting, M.D., Ormerod, K.L., Koyama, M., Olver, S.D., Straube, J., Kuns, R.D., Robb, R.J., Henden, A.S., Cooper, L., Lachner, N., Gartlan, K.H., Lantz, O., Kjer-Nielsen, L., Mak, J.Y., Fairlie, D.P., Clouston, A.D., McCluskey, J., Rossjohn, J., Lane, S.W., Hugenholtz, P. and Hill, G.R. (2018) Recipient mucosal-associated invariant T cells control GVHD within the colon. The Journal of clinical investigation 128: 10.1172/jci91646

 

Velkov, T., Gallardo-Godoy, A., Swarbrick, J.D., Blaskovich, M.A.T., Elliott, A.G., Han, M., Thompson, P.E., Roberts, K.D., Huang, J.X., Becker, B., Butler, M.S., Lash, L.H., Henriques, S.T., Nation, R.L., Sivanesan, S., Sani, M.A., Separovic, F., Mertens, H., Bulach, D., Seemann, T., Owen, J., Li, J. and Cooper, M.A. (2018) Structure, function, and biosynthetic origin of Octapeptin antibiotics active against extensively drug-resistant Gram-negative bacteria. Cell chemical biology 25: 10.1016/j.chembiol.2018.01.005

 

Verghese, D.A., Chun, N., Paz, K., Fribourg, M., Woodruff, T.M., Flynn, R., Hu, Y., Xiong, H., Zhang, W., Yi, Z., Du, J., Blazar, B.R. and Heeger, P.S. (2018) C5aR1 regulates T follicular helper differentiation and chronic graft-versus-host disease bronchiolitis obliterans. JCI insight 3: 10.1172/jci.insight.124646

 

Vuckovic, S., Minnie, S.A., Smith, D., Gartlan, K.H., Watkins, T.S., Markey, K.A., Mukhopadhyay, P., Guillerey, C., Kuns, R.D., Locke, K.R., Pritchard, A.L., Johansson, P.A., Varelias, A., Zhang, P., Huntington, N.D., Waddell, N., Chesi, M., Miles, J.J., Smyth, M.J. and Hill, G.R. (2018) Bone marrow transplantation generates T cell-dependent control of myeloma in mice. The Journal of clinical investigation 129: 10.1172/jci98888

 

Walker, M.J. and Brouwer, S. (2018) Scarlet fever makes a comeback. The Lancet. Infectious diseases 18: 10.1016/s1473-3099(17)30694-1

 

Wang, H., D'Souza, C., Lim, X.Y., Kostenko, L., Pediongco, T.J., Eckle, S.B.G., Meehan, B.S., Shi, M., Wang, N., Li, S., Liu, L., Mak, J.Y.W., Fairlie, D.P., Iwakura, Y., Gunnersen, J.M., Stent, A.W., Godfrey, D.I., Rossjohn, J., Westall, G.P., Kjer-Nielsen, L., Strugnell, R.A., McCluskey, J., Corbett, A.J., Hinks, T.S.C. and Chen, Z. (2018) MAIT cells protect against pulmonary Legionella longbeachae infection. Nature communications 9: 10.1038/s41467-018-05202-8

 

Werder, R.B., Lynch, J.P., Simpson, J.C., Zhang, V., Hodge, N.H., Poh, M., Forbes-Blom, E., Kulis, C., Smythe, M.L., Upham, J.W., Spann, K., Everard, M.L. and Phipps, S. (2018) PGD2/DP2 receptor activation promotes severe viral bronchiolitis by suppressing IFN-lambda production. Science translational medicine 10: 10.1126/scitranslmed.aao0052

 

Whiley, D.M., Jennison, A., Pearson, J. and Lahra, M.M. (2018) Genetic characterisation of Neisseria gonorrhoeae resistant to both ceftriaxone and azithromycin. The Lancet. Infectious diseases 18: 10.1016/s1473-3099(18)30340-2

 

Wright, V.J., Herberg, J.A., Kaforou, M., Shimizu, C., Eleftherohorinou, H., Shailes, H., Barendregt, A.M., Menikou, S., Gormley, S., Berk, M., Hoang, L.T., Tremoulet, A.H., Kanegaye, J.T., Coin, L.J.M., Glode, M.P., Hibberd, M., Kuijpers, T.W., Hoggart, C.J., Burns, J.C. and Levin, M. (2018) Diagnosis of Kawasaki disease using a minimal whole-blood gene expression signature. JAMA pediatrics 172: 10.1001/jamapediatrics.2018.2293

 

You, Y., Davies, M.R., Walker, M.J. and Zhang, J. (2018) Hypotheses for the resurgence of scarlet fever in China. The Lancet. Infectious diseases 18: 10.1016/s1473-3099(18)30470-5

 

Yuan, X., Johnson, M.D., Zhang, J., Lo, A.W., Schembri, M.A., Wijeyewickrema, L.C., Pike, R.N., Huysmans, G.H.M., Henderson, I.R. and Leyton, D.L. (2018) Molecular basis for the folding of beta-helical autotransporter passenger domains. Nature communications 9: 10.1038/s41467-018-03593-2

 

2017:

Rutledge, G.G., Bohme, U., Sanders, M., Rrid, A.J., Cotton, J.A., Maiga-Ascofare, O., Djimde, A.A., Apinjoh, T.O., Amenga-Etego, L., Manske, M., Barnwell, J.W., Renaud, F., Ollomo, B., Prugnolle, F., Anstey, N.M., Auburn, S., Price, R.N., McCarthy, J.S., Kwiatkowski, D.P., Newbold, C.I., Berriman, M., Otto, T.D. (2017) Plasmodium malariae and P. ovale genomes provide insights into malaria parasite evolution. Nature 542: 10.1038/nature21038

 

Chen, W.Q., Foo, S.S., Zaid, A., Teng, T.S., Herrero, L.J., Wolf, S., Tharmarajah, K., Vu, L.D., van Vreden, C., Taylor, A., Freitas, J.R., Li, R.W., Woodruff, T.M., Gordon, R., Ojcius, D.M., Nakaya, H.I., Kanneganti, T.D., O'Neill, L.A.J., Robertson, A.A.B., King, N.J., Suhrbier, A.Cooper, M.A., Ng, L.F.P., Mahalingam, S. (2017) Specific inhibition of NLRP3 in chikungunya disease reveals a role for inflammasomes in alphavirus-induced inflammation. Nature Microbiology 2: 10.1038/s41564-017-0015-4

 

Lohman, R.J., Hamidon, J.K., Reid, R.C., Rowley, J.A., Yau, M.K., Halili, M.A., Nielsen, D.S., Lim, J., Wu, K.C., Loh, Z., Do, A., Suen, J.Y., Iyer, A., Fairlie, D.P. (2017) Exploiting a novel conformational switch to control innate immunity mediated by complement protein C3a. Nature Communications 8: 10.1038/s41467-017-00414-w.

 

Furlong, E.J., Lo, A.W., Kurth, F., Premkumar, L., Totsika, M., Achard, M.E.S., Halili, M.A., Heras, B., Whitten, A.E., Choudhury, H.G., Schembri, M.A., Martin, J.L. (2017) A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance. Nature Communications 8: 10.1038/ncomms16065.

 

Adema, C.M., Hillier, L.W., Jones, C.S., Loker, E.S., Knight, M., Minx, P., Oliveira, G., Raghavan, N., Shedlock, A., do Amaral, L.R., Arican-Goktas, H.D., Assis, J.G., Baba, E.H., Baron, O.L., Bayne, C.J., Bickham-Wright, U., Biggar, K.K., Blouin, M., Bonning, B.C., Botka, C., Bridger, J.M., Buckley, K.M., Buddenborg, S.K., Caldeira, R.L., Carleton, J., Carvalho, O.S., Castillo, M.G; Chalmers, I.W., Christensens, M., Clifton, S., Cosseau, C., Coustau, C., Cripps, R.M., Cuesta-Astroz, Y., Cummins, S.F., Di Stephano, L., Dinguirard, N., Duval, D., Emrich, S., Feschotte, C., Feyereisen, R., FitzGerald, P., Fronick, C., Fulton, L., Galinier, R., Gava, S.G., Geusz, M., Geyer, K.K., Giraldo-Calderon, G.I., Gomes, M.D., Gordy, M.A., Gourbal, B., Grunau, C., Hanington, P.C. Hoffmann, K.F., Hughes, D., Humphries, J., Jackson, D.J., Jannotti-Passos, L.K., Jeremias, W.D., Jobling, S., Kamel, B., Kapusta, A., Kaur, S., Koene, J.M., Kohn, A.B., Lawson, D., Lawton, S.P., Liang, D., Limpanont, Y., Liu, S.J., Lockyer, A.E., Lovato, T.L., Ludolf, F., Magrini, V., McManus, D.P., Medina, M., Misra, M., Mitta, G., Mkoji, G.M., Montague, M.J., Montelongo, C., Moroz, L.L., Munoz-Torres, M.C., Niazi, U., Noble, L.R., Oliveira, F.S., Pais, F.S., Papenfuss, A.T., Peace, R., ; Pena, J.J., Pila, E.A., Quelais, T., Raney, B.J., Rast, J.P., Rollinson, D., Rosse, I.C., Rotgans, B., Routledge, E.J., Ryan, K.M., Scholte, L.L.S., Storey, K.B., Swain, M., Tennessen, J.A., Tomlinson, C., Trujillo, D.L., Volpi, E.V., Walker, A.J., Wang, T., Wannaporn, I., Warren, W.C., Wu, X.J., Yoshino, T.P., Yusuf, M., Zhang, S.M., Zhao, M., Wilson, R.K. (2017) Whole genome analysis of a schistosomiasis-transmitting freshwater snail. Nature Communications 8: 10.1038/ncomms15451.

 

Wang, J.P., Yu, Y., Shen, H.M., Qing, T., Zheng, Y.T., Li, Q., Mo, X.J., Wang, S.Q., Li, N.N., Chai, R.Y., Xu, B., Liu, M., Brindley, P.J., McManus, D.P., Feng, Z., Shi, L.M., Hu, W. (2017) Dynamic transcriptomes identify biogenic amines and insect-like hormonal regulation for mediating reproduction in Schistosoma japonicumNature Communications 8: 10.1038/ncomms14693.

 

Kerr, M.C., Gomez, G.A., Ferguson, C., Tanzer, M.C., Murphy, J.M., Yap, A.S., Parton, R.G., Huston, W.M., Teasdale, R.D. (2017) Laser-mediated rupture of chlamydial inclusions triggers pathogen egress and host cell necrosis Nature Communications 8: 10.1038/ncomms14729.

 

Cao, M.D., Nguyen, S.H., Ganesamoorthy, D., Elliott, A.G., Cooper, M.A.Coin, L.J.M. (2017) Scaffolding and completing genome assemblies in real-time with nanopore sequencing. Nature Communications 8: 10.1038/ncomms14515.

 

Luo, L., Bokil, N.J., Wall, A.A., Kapetanovic, R., Lansdaal, N.M., Marceline, F., Burgess, B.J., Tong, .SJ., Guo, Z., Alexandrov, K., Ross, I.L., Hibbs, M.L., Stow, J.L.Sweet, M.J. (2017) SCIMP is a transmembrane non-TIR TLR adaptor that promotes proinflammatory cytokine production from macrophages. Nature Communications 8: 10.1038/ncomms14133.

 

Zhang, P., Lee, .S., Gartlan, K.H., Schuster, I.S., Comerford, I., Varelias, A., Ullah, A., Vuckovic, S., Koyama, M., Kuns, R.D., Locke, K.R., Beckett, K.J., Olver, S.D., Samson, L.D., Montes de Oca, M., de Labastida Rivera, F., Clouston, A.D., Belz, G.T., Blazar, B.R., MacDonald, K.P., McColl, S.R., Thomas, R., Engwerda, C.R., Degli-Esposti, M.A., Kallies, A., Tey, S.K., Hill, G.R. (2017) Eomesodermin promotes the development of type 1 regulatory T (TR1) cells. Science Immunology 2: 10.1126/sciimmunol.aah7152.

 

McCarthy, J.S., Lotharius, J., Ruckle, T., Chalon, S., Phillips, M.A., Elliott, S., Sekuloski, S., Griffin, P., Ng, C.L., Fidock, D.A. (2017) Safety, tolerability, pharmacokinetics, and activity of the novel long-acting antimalarial DSM265: a two-part first-in-human phase 1a/1b randomised study. Lancet Infectious Diseases 17: 626-635.

 

Paterson, D.L., van Duin, D. (2017) China's antibiotic resistance problems. Lancet Infectious Diseases 17: 351-352.

 

2016:

 

Guillerey, C., Huntington, N.D., Smyth, M.J. (2016) Targeting natural killer cells in cancer immunotherapy, Nature Immunology 17: 1025-1036.

 

Bryant, J.M., Grogono, D.M, Rodriguez-Rincon, D., Everall, I., Brown, K.P., Moreno, P., Verma, D., Hill, E., Drijkoningen, J., Gilligan, P., Esther, C.R., Noone, P.G., Giddings, O., Bell, S.C., Thomson, R., Wainwright, C.E., Coulter, C., Pandey, S., Wood, M.E., Stockwell, R.E., Ramsay, K.A., Sherrard, L.J., Kidd, T.J., Jabbour, N., Johnson, G.R., Knibbs, L.D., Morawska, L., Sly, P.D., Jones, A., Bilton, D., Laurenson, I., Ruddy, M., Bourke, S., Bowler, I.C.J.W., Chapman, S.J., Clayton, A., Cullen, M., Dempsey, O., Denton, M., Desai, M., Drew, R.J., Edenborough, F., Evans, J., Folb, J., Daniels, T., Humphrey, H., Isalska, B., Jensen-Fangel, S., Jonsson, B., Jones, A.M., Katzenstein, T.L., Lillebaek, T., MacGregor, G., Mayell, S., Millar, M., Modha, D., Nash, E.F., O'Brien, C., O'Brien, D., Ohri, C., Pao, C.S., Peckham, D., Perrin, F., Perry, A., Pressler, T., Prtak, L., Qvist, T., Robb, A., Rodgers, H., Schaffer, K., Shafi, N., van Ingen, J., Walshaw, M., Watson, D., West, N., Whitehouse, J., Haworth, C.S., Harris, S.R., Ordway, D., Parkhill, J., Floto, R.A. (2016) Emergence and spread of a human-transmissible multidrug-resistant nontuberculous mycobacterium. Science 354: 751-757.

 

Navarro, S., Pickering, D.A., Ferreira, I.B., Jones, L., Ryan, S., Troy, S., Leech, A., Hotez, P.J., Zhan, B., Laha, T., Prentice, R., Sparwasser, T., Croese, J., Engwerda, C.R.Upham, J.W., Julia, V., Giacomin, P.R., Loukas, A. (2016) Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthma. Science Translational Medicine 8: 362ra143.

 

Hall, R.A., Macdonald, J. (2016) Synthetic biology provides a toehold in the fight against Zika. Cell Host Microbe 19: 752-754.

 

Trembizki, E., Guy, R., Donovan, B., Kaldor, J.M., Lahra, M.M., Whiley, D.M. (2016) Further evidence to support the individualised treatment of gonorrhoea with ciprofloxacin. Lancet Infectious Diseases 16: 1005-1006.

Paterson, D.L., Harris, P.N.A. (2016) Colistin resistance: a major breach in our last line of defence. Lancet Infectious Diseases 16: 132-133.

 

Stubenrauch, C., Belousoff, M.J., Hay, I.D., Shen, H.H., Lillington, J., Tuck, K.L., Peters, K.M., Phan, M.D., Lo, A.W., Schembri, M.A., Strugnell, R.A., Waksman, G., Lithgow, T. (2016) Less Effective assembly of fimbriae in Escherichia coli depends on the translocation assembly module nanomachine. Nature Microbiology 7: 16064.

 

 2015:

 

Coll, R.C., Robertson, A.A.B., Chae, J.J., Higgins, S.C., Munoz-Planillo, R., Inserra, M.C., Vetter, I., Dungan, L.S., Monks, B.G., Stutz, A., Croker, D.E., Butler, M.S., Haneklaus, M., Sutton, C.E., Nunez, G., Latz, E., Kastner, D.L., Mills, K.H.G., Masters, S.L., Schroder, K.Cooper, M.A., O'Neill, L.A.J. (2015) A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases. Nature Medicine 21: 248-255.

 

Zuegg, J., Muldoon, C., Adamson, G., McKeveney, D., Le Thanh, G., Premraj, R., Becker, B., Cheng, M., Elliott, A.G., Huang, J.X., Butler, M.S., Bajaj, M., Seifert, J., Singh, L., Galley, N.F., Roper, D.I, Lloyd, A.J., Dowson, C.G., Cheng, T.J., Cheng, W.C., Demon, D., Meyer, E., Meutermans, W., Cooper, M.A. (2015) Carbohydrate scaffolds as glycosyltransferase inhibitors with in vivo antibacterial activity. Nature Communications 6: 7719.

 

Cooper, M.A. (2015) A community-based approach to new antibiotic discovery. Nature Reviews Drug Discovery 14: 587-588.

 

Davies, M.R., Holden, M.T., Coupland, P., Chen, J.H.K., Venturini, C., Barnett, T.C., Ben Zakour, N., Tse, H., Dougan, G., Yuen, K.Y., Walker, M.J. (2015) Emergence of scarlet fever Streptococcus pyogenes M12 clones in Hong Kong is associated with toxin acquisition and multi-drug resistance. Nature Genetics 47: 84-87.

 

Teng, M.W.L, Bowman, E.P., McElwee, J.J., Smyth, M.J., Casanova, J.L., Cooper, A.M., Cua, D.J. (2015) IL-12 and IL-23 cytokines: from discovery to targeted therapies for immune-mediated inflammatory diseases. Nature Medicine 21: 719-729.

 

Zowawi, H.M., Harris, P.N.A., Roberts, M.J., Tambyah, P.A., Schembri, M.A., Pezzani, M.D., Williamson, D.A, Paterson, D.L. (2015) The emerging threat of multidrug-resistant Gram-negative bacteria in urology. Nature Reviews Urology 12: 570-584.

 

Martinet, L., Smyth, M.J. (2015) Balancing natural killer cell activation through paired receptors. Nature Reviews Immunology 15: 243-254.

 

Zitvogel, L., Galluzzi, L., Kepp, O., Smyth, M.J., Kroemer, G. (2015) Type I interferons in anticancer immunity. Nature Reviews Immunology 15: 405-414.

 

Modhiran, N., Watterson, D., Muller, D.A., Panetta, A.K., Sester, D.P., Liu, L.D., Hume, D.A., Stacey, K.J.Young, P.R. (2015) Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity. Science Translational Medicine 7: 304ra142.

 

Wainwright, C.E., Elborn, J.S., Ramsey, B.W., Marigowda, G., Huang, X., Cipolli, M., Colombo, C., Davies, J.C., De Boeck, K., Flume, P.A., Konstan, M.W., McColley, S.A., Mccoy, K., McKone, E.F., Munck, A., Ratjen, F., Rowe, S.M., Waltz, D., Boyle, M.P. (2015) Lumacaftor-Ivacaftor in patients with cystic Fibrosis homozygous for Phe508del CFTR. New England Journal of Medicine 373: 220-231.

 

Rampatige, R., Gilks, C.F. (2015) Autopsies and better data on causes of death in Africa. Lancet Infectious Diseases 15: 492-494.

 

Harris, P.N.A., Tambyah, P.A., Paterson, D.L. (2015) Beta-lactam and beta-lactamase inhibitor combinations in the treatment of extended-spectrum beta-lactamase producing Enterobacteriaceae: time for a reappraisal in the era of few antibiotic options? Lancet Infectious Diseases 15: 475-485.

 

Schlapbach, L.J., Straney, L., Alexander, J., MacLaren, G., Festa, M., Schibler, A., Slater, A., (2015) Mortality related to invasive infections, sepsis, and septic shock in critically ill children in Australia and New Zealand, 2002-13: a multicentre retrospective cohort study. Lancet Infectious Diseases 15: 46-54.

 

2014:

 

Corbett, A.J., Eckle, S.B., Birkinshaw, R.W., Liu, L., Patel, O., Mahony, J., Chen, Z., Reantragoon, R., Meehan, B., Cao, H., Williamson N.A., Strugnell, R.A, Van Sinderen, D., Mak, J.Y., Fairlie, D.P., Kjer-Nielsen, L., Rossjohn, J., McCluskey, J. (2014) T-cell activation by transitory neo-antigens derived from distinct microbial pathways. Nature 509: 361-365.

 

Goire, N., Lahra, M.M., Chen, M., Donovan, B., Fairley, C.K., Guy, R., Kaldor, J., Regan, D., Ward, J., Nissen, M.D., Sloots, T.P., Whiley, D.M. (2014) Molecular approaches to enhance surveillance of gonococcal antimicrobial resistance. Nature Reviews Microbiology 12: 223-229. 

 

Counago, R.M., Ween, M.P., Begg, S.L., Bajaj, M., Zuegg, J., O'Mara, M.L., Cooper, M.A., McEwan, A.G., Paton, J.C., Kobe, B., McDevitt, C.A. (2014) Imperfect coordination chemistry facilitates metal ion release in the Psa permease. Nature Chemical Biology 10: 35-66U. 

 

Dacunha, V., Davies, M.R., Douarre, P.E., Rosinski-Chupin, I., Margarit, I., Spinali, S., Perkins, T., Lechat, P., Dmytruk, N., Sauvage, E., Ma, L., Tichit, M., Lopez-Sanchez, M.J., Descorps-Declere, S., Buchrieser, C., Trieu-Cuot, P., Moszer, I., Clermont, D., Maione, D., Bouchier, C., McMillan, D.J., Parkhill, J., Telford, J.L., Dougan, G., Walker, M.J., The Devani Consortium, Holden, M.T.G., Poyart C., Glaser P. (2014) Streptococcus agalactiae clones infecting humans have been selected and fixed through the extensive use of tetracycline. Nature Communications 5: 4544. 

 

Milinovich, G.J., Williams, G.M., Clements, A.C.A., Hu, W.B. (2014) Internet-based surveillance systems for monitoring emerging infectious diseases. Lancet Infectious Diseases 14:160-168.

 

Beatson, S.A., Walker, M.J. (2014) Tracking antibiotic resistance. Science 345: 1454-1455.

 

van Sorge, N.M., Cole, J.N., Kuipers, K., Henningham, A., Aziz, R.K., Kasirer-Friede, A., Lin, L., Berends, E.T.M., Davies, M.R., Dougan, G., Zhang, F., Dahesh, S., Shaw, L., Gin, J., Cunningham, M., Merriman, J.A., Rooijakkers, S.H.M., Malley, R., Walker, M.J., Shattil, S.J., Schlievert, P.M., Choudhury, B, Nizet, V. (2014) The classical Lancefield antigen of group A Streptococcus is a virulence determinant with implications for vaccine design. Cell Host & Microbe 15: 729-740.

 

2013:

 

Clements, A.C.A., Reid, H.L., Kelly, G.C., Hay, S.I. (2013) Further shrinking the malaria map: how can geospatial science help to achieve malaria elimination? Lancet Infectious Diseases 13: 709-718.

 

Barnett, T.C., Liebl, D., Seymour, L.M., Gillen, C.M., LaRock, C.N., Davies, M.R., Schulz, B.L., Nizet, V., Teasdale, R.D., Walker, M.J. (2013) The group A Streptococcus M1T1 clone evades autophagy for intracellular replication. Cell Host & Microbe 14: 675-682.

 

Truong, N.P., Gu, W.Y., Prasadam, I., Jia, Z.F., Crawford, R., Xiao, Y., Monteiro, M.J. (2013) An influenza virus-inspired polymer system for the timed release of siRNA. Nature Communications 4: 1902.

 

Reid, R.C., Yau, M.K., Singh, R., Hamidon, J.K., Reed, A.N., Chu, P., Suen, J.Y., Stoermer, M.J., Blakeney, J.S., Lim, J., Faber, J.M., Fairlie, D.P. (2013) Downsizing a human inflammatory protein to a small molecule with equal potency and functionality. Nature Communications 4: 3802.

 

2012:

Mahalingam, S, Herrero, L.J., Playford, E.G., Spann, K.M., Herring, B., Rolph, M.S., Middleton, D., McCall, B., Field, H., Wang, L.F. (2012) Hendra virus: an emerging paramyxovirus in Australia. Lancet Infectious Diseases 12: 799-807.

 

Richmond, P.C., Marshall, H.S., Nissen, M.D., Jiang, Q., Jansen, K.U., Garcés-Sánchez, M., Martinón-Torres, F., Beeslaar, J., Szenborn, L., Wysocki, J., Eiden, J., Harris, S.L., Jones, T.R., Perez, J.L. (2012) Safety, immunogenicity, and tolerability of meningococcal serogroup B bivalent recombinant lipoprotein 2086 vaccine in healthy adolescents: a randomised, single-blind, placebo-controlled, phase 2 trial. Lancet Infectious Diseases 12: 597–607.

 

Selkrig J., Mosbahi K., Webb C.T., Belousoff M.J., Perry A.J., Wells T.J., Morris F., Leyton D.L., Totsika M., Phan M.D., Celik N., Kelly M., Oates C., Hartland E.L., Robins-Browne R.M., Ramarathinam S.H., Purcell A.W., Schembri M.A., Strugnell R.A., Henderson I.R., Walker D., Lithgow T. (2012) Discovery of an archetypal protein transport system in bacterial outer membranes. Nature Structural & Molecular Biology 19: 506-510.

 

Holt, P.G., Sly, P.D. (2012) Viral infections and atopy in asthma pathogenesis: new rationales for asthma prevention and treatment. Nature Medicine 18: 726-735. 

 

Walker, M.J., Beatson, S.A. (2012) Outsmarting outbreaks. Science 338: 1039-1040. 

 

2011:

Ramsey, B.W., Davies, J., McElvaney N.G., Tullis, E., Bell, S.C., Dřevínek, P., Griese, M., McKone, E., Wainwright, C., Konstan, M., Moss, R., Ratjen, F., Sermet-Gaudelus, I., Rowe, S.M., Dong, Q., Rodriguez, S., Yen, K., Ordoñez, C., Elborn, J.S. on behalf of the VX08-770-102 Study Group. (2011) A CFTR potentiator in patients with cystic fibrosis and the G551D Mutation. New England Journal of Medicine 365: 1663-1672.

 

Deng, Z.J., Liang, M.T., Monteiro, M., Toth, I., Minchin, R.F. (2011) Nanoparticle-induced unfolding of fibrinogen promotes Mac-1 (CD11b/CD18) receptor activation and inflammation. Nature Nanotechnology 6: 39-44.

 

Cole, J.N., Barnett, T.C., Nizet, V., Walker, M.J. (2011) Molecular insight into group A streptococcal invasive disease. Nature Reviews Microbiology 9: 1-13.

 

Gavidia, T., Brune, M.N., McCarty, K.M., Pronczuk, J., Etzel, R., Neira, M., Carpenter, D.O., Suk, W.A., Arnold, R.G., Ha, E.H., Sly, P.D. (2011) Children's environmental health - from knowledge to action. Lancet 377: 1134-1136.

 

Cooper, M.A., Shlaes, D.A. (2011) Fix the antibiotics pipeline. Nature 472: 32.

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