AID researchers are drawn from infectious disease experts from across QIMR and UQ who apply leading technologies to identify, understand and prevent infectious disease.
Dr Simone Reynolds
Dr Simone Reynolds is a Research Fellow, Laboratory of Vaccines for the Developing World, Griffith University and Affiliate Scientist at QIMR Berghofer Medical Research Institute. Her research focuses on the development of a vaccine against the bacterial pathogen Streptococcus pyogenes (Strep A) to prevent skin and mucosal streptococcal infections and which plays a critical role in the development of rheumatic fever and rheumatic heart disease. Her work involves pre-clinical evaluation of vaccine candidates in mice, exploring alternative methods for vaccine delivery and clinical trials in humans. Dr Reynolds has skills in molecular biology, biochemistry, human immunology and project management.
She was previously a Research Officer at QIMR Berghofer, where she worked in the Scabies Group. Her research focused on a family of scabies mite proteins that interact with a component of the human immune system called Complement. She has shown that these scabies mite anti-Complement proteins help the mites to evade host immunity and establish infection. The Scabies Group have also shown that these proteins help to promote the growth of pathogenic bacteria commonly associated with scabies sores, including Streptococcus pyogenes. The overall aim was to find suitable targets for developing therapeutics for scabies that simultaneously reduces the occurrence of secondary bacterial infections, including Strep A.