Established in 2011, the Australian Infectious Diseases Research Centre is a multidisciplinary network based at The University of Queensland, and the QIMR Berghofer Medical Research Institute.
Dr Ashraful Haque (NHMRC CDF)
Dr Haque researches the interactions that occur between the malaria-causing parasite,Plasmodium, and cells of the mammalian immune system.
Symptoms of malaria in humans occur after the parasite infects red blood cells, with severe, and fatal disease often occurring in patients with the largest numbers of parasites in their bodies.
His aim is to understand how infected red blood cells can be detected and cleared from the body by the immune system, and importantly, why this process so often fails.
Dr Haque researches novel strategies for improving parasite clearance, to inform the development of better vaccines and immune-therapies against malaria.
His approach has been to generate new tools and techniques to study Plasmodium parasites in well-established experimental malaria models.
He is currently focused on understanding how Plasmodium interactions with dendritic cells and macrophages controls both the outcome of infection, and the onset of adaptive immunity to malaria.